Chemical characters and antioxidative properties of sulfated polysaccharides from Laminaria japonica

被引:180
作者
Xue, CH [1 ]
Fang, Y [1 ]
Lin, H [1 ]
Chen, L [1 ]
Li, ZJ [1 ]
Deng, D [1 ]
Lu, CX [1 ]
机构
[1] Ocean Univ Qingdao, Dept Food Sci & Technol, Qingdao 266003, Shandong, Peoples R China
关键词
antioxidant; chemical characters; fucoidan; Laminaria japonica; LDL; low-density lipoprotein;
D O I
10.1023/A:1008103611522
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A low molecular weight sulfated polysaccharide (L-A) was prepared by mild acid hydrolysis of crude fucoidan (F-A) from Laminaria japonica. In comparison with F-A, L-A had a lower proportion of fucose residues, but a similar proportion of sulfate. The galactose content of both fractions was relatively high, especially for L-A (57%). The antioxidant properties of the two polysaccharides were studied using two low-density lipoprotein oxidation systems. L-A had a stronger effect against low-density lipoprotein oxidation in both systems. F-A inhibited the AAPH-induced low-density lipoprotein oxidation, but had little effect on the Cu++-induced system due to its large molecular mass. The active sulfated fraction L-A, containing galactose, mannose and fucose (about 9: 2: 2) is reported here for the first time.
引用
收藏
页码:67 / 70
页数:4
相关论文
共 33 条
[31]  
YAMAMOTO I, 1984, JPN J EXP MED, V54, P143
[32]  
ZHANG LH, 1989, PROGR BIOCH BIOPHYS, V21, P257
[33]   ANTITUMOR ACTIVE FUCOIDAN FROM THE BROWN SEAWEED, UMITORANOO (SARGASSUM-THUNBERGII) [J].
ZHUANG, C ;
ITOH, H ;
MIZUNO, T ;
ITO, H .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1995, 59 (04) :563-567