magnetic resonance spectroscopy;
brain metabolism;
brain rumours;
D O I:
10.1007/BF00873976
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Proton magnetic resonance spectroscopy (H-1-MRS) was applied to characterize intracranial tumours of different hystological types. Seventy patients with intracranial neoplasms were studied before receiving surgery radiotherapy or chemotherapy. All tumours were characterized by reduced or absent N-acetylaspartate and increased signal from choline-containing compounds. Distinctive patterns were observed only for primitive brain neoplasms; high-grade gliomas were differentiated From low-grade ones by higher levels of choline-containing compounds. The metabolic aspects of metastatic lesions were similar to high-grade gliomas. These results, together with the limitations of H-1-MRS and future applications are reviewed.