Stillbirths 4 Stillbirths: how can health systems deliver for mothers and babies?

被引:135
作者
Pattinson, Robert [1 ]
Kerber, Kate [2 ]
Buchmann, Eckhart [3 ,4 ]
Friberg, Ingrid K. [5 ]
Belizan, Maria [1 ,6 ]
Lansky, Sonia [7 ]
Weissman, Eva [8 ]
Mathai, Matthews [9 ]
Rudan, Igor [10 ,11 ]
Walker, Neff [5 ]
Lawn, Joy E. [2 ,12 ,13 ]
机构
[1] Univ Pretoria, Dept Obstet & Gynaecol, Med Res Council Maternal & Infant Hlth Care Strat, ZA-0001 Pretoria, South Africa
[2] Saving Newborn Lives Save Children, Cape Town, South Africa
[3] Chris Hani Baragwanath Hosp, Dept Obstet & Gynaecol, Johannesburg, South Africa
[4] Univ Witwatersrand, Johannesburg, South Africa
[5] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
[6] Inst Clin Effectiveness & Hlth Policy, Buenos Aires, DF, Argentina
[7] Univ Fed Minas Gerais, Belo Horizonte Hlth Dept, Belo Horizonte, MG, Brazil
[8] Futures Inst, New York, NY USA
[9] WHO, Dept Maternal Newborn Child & Adolescent Hlth, CH-1211 Geneva, Switzerland
[10] Univ Split, Sch Med, Croatian Ctr Global Hlth, Split, Croatia
[11] Univ Edinburgh, Sch Med, Ctr Populat Hlth Sci, Edinburgh, Midlothian, Scotland
[12] MRC, Hlth Syst Res Unit, Cape Town, South Africa
[13] Inst Child Hlth, London, England
基金
比尔及梅琳达.盖茨基金会;
关键词
MATERNAL MORTALITY; CHILD HEALTH; OBSTETRIC CARE; GLOBAL HEALTH; PRETERM BIRTH; NEWBORN; INTERVENTIONS; CHALLENGES; FACILITIES; CONTINUUM;
D O I
10.1016/S0140-6736(10)62306-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The causes of stillbirths are inseparable from the causes of maternal and neonatal deaths. This report focuses on prevention of stillbirths by scale-up of care for mothers and babies at the health-system level, with consideration for effects and cost. In countries with high mortality rates, emergency obstetric care has the greatest effect on maternal and neonatal deaths, and on stillbirths. Syphilis detection and treatment is of moderate effect but of lower cost and is highly feasible. Advanced antenatal care, including induction for post-term pregnancies, and detection and management of hypertensive disease, fetal growth restriction, and gestational diabetes, will further reduce mortality, but at higher cost. These interventions are best packaged and provided through linked service delivery methods tailored to suit existing health-care systems. If 99% coverage is reached in 68 priority countries by 2015, up to 1.1 million (45%) third-trimester stillbirths, 201000 (54%) maternal deaths, and 1.4 million (43%) neonatal deaths could be saved per year at an additional total cost of US$10.9 billion or $2.32 per person, which is in the range of $0.96-2.32 for other ingredients-based intervention packages with only recurrent costs.
引用
收藏
页码:1610 / 1623
页数:14
相关论文
共 62 条
[31]   Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial [J].
Davies, M. J. ;
Heller, S. ;
Skinner, T. C. ;
Campbell, M. J. ;
Carey, M. E. ;
Cradock, S. ;
Dallosso, H. M. ;
Daly, H. ;
Doherty, Y. ;
Eaton, S. ;
Fox, C. ;
Oliver, L. ;
Rantell, K. ;
Rayman, G. ;
Khunti, K. .
BMJ-BRITISH MEDICAL JOURNAL, 2008, 336 (7642) :491-495
[32]   Stillbirths 5 Stillbirths: the way forward in high-income countries [J].
Flenady, Vicki ;
Middleton, Philippa ;
Smith, Gordon C. ;
Duke, Wes ;
Erwich, Jan Jaap ;
Khong, T. Yee ;
Neilson, Jim ;
Ezzati, Majid ;
Koopmans, Laura ;
Ellwood, David ;
Fretts, Ruth ;
Froen, J. Frederik .
LANCET, 2011, 377 (9778) :1703-1717
[33]   Stillbirths 1 Stillbirths: why they matter [J].
Froen, J. Frederik ;
Cacciatore, Joanne ;
McClure, Elizabeth M. ;
Kuti, Oluwafemi ;
Jokhio, Abdul Hakeem ;
Islam, Monir ;
Shiffman, Jeremy .
LANCET, 2011, 377 (9774) :1353-1366
[34]  
Hodnett ED, 2011, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD003766.pub3, 10.1002/14651858.CD003766.pub2, 10.1002/14651858.CD003766.pub4, 10.1002/14651858.CD003766.pub5, 10.1002/14651858.CD003766.pub6]
[35]   Obstetric care in low-resource settings: What, who, and how to overcome challenges to scale up? [J].
Hofmeyr, G. Justus ;
Haws, Rachel A. ;
Bergstroem, Staffan ;
Lee, Anne C. C. ;
Okong, Pius ;
Darmstadt, Gary L. ;
Mullany, Luke C. ;
Oo, Eh Kalu Shwe ;
Lawn, Joy E. .
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2009, 107 :S21-S45
[36]   An intervention involving traditional birth attendants and perinatal and maternal mortality in Pakistan [J].
Jokhio, AH ;
Winter, HR ;
Cheng, KK .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (20) :2091-2099
[37]   Continuum of care for maternal, newborn, and child health: from slogan to service delivery [J].
Kerber, Kate J. ;
de Graft-Johnson, Joseph E. ;
Bhutta, Zulfiqar A. ;
Okong, Pius ;
Starrs, Ann ;
Lawn, Joy E. .
LANCET, 2007, 370 (9595) :1358-1369
[38]   Sub-Saharan Africa's Mothers, Newborns, and Children: Where and Why Do They Die? [J].
Kinney, Mary V. ;
Kerber, Kate J. ;
Black, Robert E. ;
Cohen, Barney ;
Nkrumah, Francis ;
Coovadia, Hoosen ;
Nampala, Paul Michael ;
Lawn, Joy E. .
PLOS MEDICINE, 2010, 7 (06)
[39]   The impact of conditional cash transfers on health outcomes and use of health services in low and middle income countries [J].
Lagarde, Mylene ;
Haines, Andy ;
Palmer, Natasha .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2009, (04)
[40]   Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes [J].
Lassi, Zohra S. ;
Bhutta, Zulfiqar A. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2015, (03)