Seleno-imine: A new class of versatile, modular N,Se ligands for asymmetric palladium-catalyzed allylic alkylation

被引：65

作者：

Braga, AL ^{[1
]}

Paixao, MW ^{[1
]}

Marin, G ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

来源：

SYNLETT | 2005年 / 11期

关键词：

seleno-imines; allylic alkylations; palladium-catalyzed;

D O I：

10.1055/s-2005-871546

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate in the presence of chiral seleno-imine ligands derived from an inexpensive and easily available chiral pool was investigated. Excellent yield and enantioselectivity (up to 97% ee) was achieved when ligand 4a was used.

引用

页码：1675 / 1678

页数：4

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