A novel catalytic process for trifluoromethylation of bromoaromatic compounds

被引：58

作者：

Samant, Bhupesh S. ^{[1
]}

Kabalka, George W. ^{[2
,3
,4
]}

机构：

[1] Rhodes Univ, Div Pharmaceut Chem, Fac Pharm, ZA-6140 Grahamstown, South Africa

[2] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA

[3] Univ Tennessee, Dept Radiol, Knoxville, TN 37996 USA

[4] UT Med Hosp, Biomed Imaging Ctr, Knoxville, TN 37920 USA

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 25期

关键词：

FORMING REDUCTIVE ELIMINATION; ASYMMETRIC FLUORINATION; AROMATIC-COMPOUNDS; RADICALS; AGENTS; COPPER;

D O I：

10.1039/c1cc12098k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The palladium-catalyzed trifluoromethylation of aryl bromides has been achieved in micellar media. The micellar conditions result in enhanced yields and are applicable to bromoaromatics with ketone, aldehyde, hydroxyl and amine functionalities.

引用

页码：7236 / 7238

页数：3

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