Anti-angiogenic, antioxidant and xanthine oxidase inhibition activities of the mushroom Phellinus linteus

被引：136

作者：

Song, YS

Kim, SH

Sa, JH

Jin, C

Lim, CJ

Park, EH ^{[1
]}

机构：

[1] Sookmyung Womens Univ, Coll Pharm, Seoul 140742, South Korea

[2] Korea Inst Sci & Technol, Bioanal & Biotransformat Res Ctr, Seoul 130650, South Korea

[3] Kangwon Res Inst Hlth & Environm, Dept Food & Drug Anal, Chunchon 200093, South Korea

[4] Kangweon Natl Univ, Div Life Sci, Chunchon 200701, South Korea

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2003年 / 88卷 / 01期

关键词：

Phellinus linteus; antioxidant activity; xanthine oxidase inhibition; anti-angiogenic activity; folk medicine;

D O I：

10.1016/S0378-8741(03)00178-8

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Fruiting bodies of Phellinus linteus were extracted with 70% ethanol at room temperature. The Phellinus linteus extract (PL) showed strong anti-angiogenic activity, which was detected using the chick embryo chorioallantoic membrane (CAM) assay. The in vitro antioxidant activities of PL were evaluated using two different bioassays. PL was comparable to Vitamin C in scavenging the stable free radical 1,1-diphenyl-2-picrylhyrazyl (DPPH). It also inhibited lipid peroxidation (LPO) in a concentration-dependent manner. These results suggest that antioxidant and anti-angiogenic activities of Phellinus linteus would be partly responsible for its anti-tumor effect. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：113 / 116

页数：4

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