Strategy for randomised clinical trials in rare cancers

被引：56

作者：

Tan, SB

Dear, KBG

Bruzzi, P

Machin, D

机构：

[1] Natl Canc Ctr, Div Clin Trials & Epidemiol Sci, Singapore 169610, Singapore

[2] Australian Natl Univ, Natl Ctr Epidemiol & Populat Hlth, Canberra, ACT, Australia

[3] Natl Inst Canc Res, Unit Clin Epidemiol & Trials, Genoa, Italy

[4] Univ Leicester, UK Childrens Canc Study Grp, Leicester, Leics, England

来源：

BRITISH MEDICAL JOURNAL | 2003年 / 327卷 / 7405期

关键词：

D O I：

10.1136/bmj.327.7405.47

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：47 / 49

页数：3

共 15 条

[1] On the use of surrogate end points in randomized trials [J].

Begg, CB ;

Leung, DHY .

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 2000, 163 :15-24

[2] Why ''underpowered'' trials are not necessarily unethical [J].

Edwards, SJL ;

Lilford, RJ ;

Braunholtz, D ;

Jackson, J .

LANCET, 1997, 350 (9080) :804-807

[3] Surrogate end points in clinical trials: Are we being misled? [J].

Fleming, TR ;

DeMets, DL .

ANNALS OF INTERNAL MEDICINE, 1996, 125 (07) :605-613

[4] Assessing the quality of reports of randomized clinical trials: Is blinding necessary? [J].

Jadad, AR ;

Moore, RA ;

Carroll, D ;

Jenkinson, C ;

Reynolds, DJM ;

Gavaghan, DJ ;

McQuay, HJ .

CONTROLLED CLINICAL TRIALS, 1996, 17 (01) :1-12

[5]

Lilford R, 2002, BRIT J SURG, V89, P129

[6] Clinical trials and rare diseases: A way out of a conundrum [J].

Lilford, RJ ;

Thornton, JG ;

Braunholtz, D .

BMJ-BRITISH MEDICAL JOURNAL, 1995, 311 (7020) :1621-1625

[7] THE WHAT, WHY AND HOW OF BAYESIAN CLINICAL-TRIALS MONITORING - DISCUSSION [J].

MACHIN, D .

STATISTICS IN MEDICINE, 1994, 13 (13-14) :1385-1389

[8] Monitoring of large randomised clinical trials: a new approach with Bayesian methods [J].

Parmar, MKB ;

Griffiths, GO ;

Spiegelhalter, DJ ;

Souhami, RL ;

Altman, DG ;

van der Scheuren, E .

LANCET, 2001, 358 (9279) :375-381

[9] THE CHART TRIALS - BAYESIAN DESIGN AND MONITORING IN PRACTICE [J].

PARMAR, MKB ;

SPIEGELHALTER, DJ ;

FREEDMAN, LS .

STATISTICS IN MEDICINE, 1994, 13 (13-14) :1297-1312

[10] DESIGN AND ANALYSIS OF RANDOMIZED CLINICAL-TRIALS REQUIRING PROLONGED OBSERVATION OF EACH PATIENT .2. ANALYSIS AND EXAMPLES [J].

PETO, R ;

PIKE, MC ;

ARMITAGE, P ;

BRESLOW, NE ;

COX, DR ;

HOWARD, SV ;

MANTEL, N ;

MCPHERSON, K ;

PETO, J ;

SMITH, PG .

BRITISH JOURNAL OF CANCER, 1977, 35 (01) :1-39

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