RuCl3 catalyzed one-pot synthesis of α-aminonitriles

被引:80
作者
De, SK
机构
[1] Dept. Med. Chem./Molec. Pharmacol., Purdue Cancer Center, Purdue University, West Lafayette
关键词
aldehydes; amines; trimethylsilyl cyanide; alpha-aminonitriles; ruthenium trichloride;
D O I
10.1081/SCC-200050347
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple and efficient method was developed for the synthesis of alpha-aminonitriles by simply mixing aldehydes, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of RuCl3 at room temperature.
引用
收藏
页码:653 / 656
页数:4
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