Pregnancy-induced changes in cell-fate in the mammary gland

被引：28

作者：

Ginger, MR ^{[1
]}

Rosen, JM ^{[1
]}

机构：

[1] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA

来源：

BREAST CANCER RESEARCH | 2003年 / 5卷 / 04期

关键词：

breast cancer; cell fate; epigenetic; mechanism; pregnancy; protection;

D O I：

10.1186/bcr603

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The protective effect of an early full-term pregnancy is a well established phenomenon; in contrast, the molecular and cell-specific mechanisms that govern parity-specific changes in the mammary gland have not been well described. Recent studies signify a dramatic advance in our understanding of this phenomenon, and indicate a 'cell fate' model for parity-related changes that lead to protection against breast cancer.

引用

页码：192 / 197

页数：6

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