Electrodeposition of chitosan-hemoglobin films

被引：32

作者：

Li, Y. ^{[1
]}

Pang, X. ^{[1
]}

Epand, R. F. ^{[2
]}

Zhitomirsky, I. ^{[1
]}

机构：

[1] McMaster Univ, Dept Mat Sci & Engn, Hamilton, ON L8S 4L7, Canada

[2] McMaster Univ, Dept Biochem & Biomed Sci, Hamilton, ON L8S 4L7, Canada

来源：

MATERIALS LETTERS | 2011年 / 65卷 / 10期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Electrodeposition; Chitosan; Hemoglobin; Film; Biosensor; ELECTROPHORETIC DEPOSITION; DIRECT ELECTROCHEMISTRY;

D O I：

10.1016/j.matlet.2011.02.038

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Electrochemical method has been developed for the fabrication of chitosan-hemoglobin films. The proposed deposition mechanism involved pH changes at the electrode surface attributed to electrochemical reactions, electrophoretic motion of cationic chitosan and hemoglobin macromolecules, coagulation and film formation at the electrode surface. The results of deposition yield measurements, and Fourier transform infrared spectroscopy and circular dichroism spectroscopy studies showed the formation of composite films containing hemoglobin in a chitosan matrix. Electron microscopy studies showed that the film thickness can be varied in the range of 0-2 mu m by the variation of deposition time at a constant deposition voltage. The films were investigated for applications in biosensors. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：1463 / 1465

页数：3

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