Biomedical applications of chitin and chitosan based nanomaterials-A short review

被引：981

作者：

Jayakumar, R. ^{[1
]}

Menon, Deepthy ^{[1
]}

Manzoor, K. ^{[1
]}

Nair, S. V. ^{[1
]}

Tamura, H. ^{[2
,3
]}

机构：

[1] Amrita Vishwa Vidyapeetham Univ, Amrita Ctr Nanosci, Amrita Inst Med Sci & Res Ctr, Kochi 682041, India

[2] Kansai Univ, Fac Chem & Mat & Bioengn, Osaka 5648680, Japan

[3] Kansai Univ, HRC, Osaka 5648680, Japan

来源：

CARBOHYDRATE POLYMERS | 2010年 / 82卷 / 02期

关键词：

Chitin; Chitosan; Nanofibers; Nanoparticles; Nanocomposite scaffolds; Tissue engineering; Drug delivery; Cancer diagnosis; Wound healing; COMPOSITE SCAFFOLDS; DEGRADATION BEHAVIOR; BIOACTIVE-GLASSES; TISSUE; NANOPARTICLES; MEMBRANES;

D O I：

10.1016/j.carbpol.2010.04.074

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Chitin and chitosan are biopolymers having immense structural possibilities for chemical and mechanical modifications to generate novel properties, functions and applications especially in biomedical area. Chitin and chitosan are effective materials for biomedical applications because of their biocompatibility, biodegradability and non-toxicity, apart from their antimicrobial activity and low immunogenicity, which clearly points to an immense potential for future development. These candidate biopolymers can be easily processed into gels, sponges, membranes, beads and scaffolds forms. This review emphasizes recent research on different aspects of chitin and chitosan based nanomaterials, including the preparation and applications of chitin and chitosan based nanofibers, nanoparticles and nanocomposite scaffolds for tissue engineering, wound dressing, drug delivery and cancer diagnosis. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：227 / 232

页数：6

共 49 条

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