Tunable acoustophoretic band-pass particle sorter

被引：39

作者：

Adams, Jonathan D. ^{[3
]}

Soh, H. Tom ^{[1
,2
]}

机构：

[1] Univ Calif Santa Barbara, Dept Mech Engn, Santa Barbara, CA 93106 USA

[2] Univ Calif Santa Barbara, Dept Mat, Santa Barbara, CA 93106 USA

[3] Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA

来源：

APPLIED PHYSICS LETTERS | 2010年 / 97卷 / 06期

基金：

美国国家卫生研究院;

关键词：

acoustic filters; electrophoresis; microchannel flow; particle size; MAMMALIAN-CELLS; FLOW; SYNCHRONIZATION; SEPARATION;

D O I：

10.1063/1.3467259

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Acoustophoretic separation in microchannels offers a promising avenue for high-throughput, label-free, cell and particle separation for many applications. However, previous acoustophoretic separation approaches have been limited to a single size separation threshold, analogous to a binary filter, (i.e., high-pass or low-pass). Here, we describe a tunable acoustophoretic separation architecture capable of sorting cells and particles based on a range of sizes, analogous to a band-pass filter. The device is capable of sorting an arbitrary range of particle sizes between 3 and 10 mu m in diameter with high efficiency (transfer fraction=0.98 +/- 0.02) at a throughput of similar to 10(8) particles/h/microchannel. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3467259]

引用

页数：3

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