Helicobacter pylori treatment:: A role for probiotics?

被引:21
作者
Cremonini, F [1 ]
Canducci, F [1 ]
Di Caro, S [1 ]
Santarelli, L [1 ]
Armuzzi, A [1 ]
Gasbarrini, G [1 ]
Gasbarrini, A [1 ]
机构
[1] Policlin Gemelli, Ist Patol Med, I-00168 Rome, Italy
关键词
Helicobacter pylori; probiotics; lactobacillus;
D O I
10.1159/000050669
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Many new therapeutic strategies are studied to improve Helicobacter pylori eradication rate. Probiotics are live microorganisms which, upon administration, may interact with the human microflora and positively affect the health status. The use of probiotics in the field of H. pylori infection has been proposed for improving eradication rate and tolerability and for compliance of multiple antibiotic regimens used for the infection. Results from laboratory studies and from clinical trials seem to confirm the expectancies, but there is lack of standardization in terms of type of probiotic strain used, dosage and timing of supplementation. Before further ongoing trials and future studies will clarify these points, probiotics could remain a useful adjunct to standard anti-H. pylori therapies, but cannot take the place of other validated options. Copyright (C) 2001 S. Karger AG, Basel.
引用
收藏
页码:144 / 147
页数:4
相关论文
共 17 条
[11]  
Isolauri E, 2001, AM J CLIN NUTR, V73, p444S, DOI 10.1093/ajcn/73.2.444s
[12]   Prevention of Helicobacter pylori infection by lactobacilli in a gnotobiotic murine model [J].
Kabir, AMA ;
Aiba, Y ;
Takagi, A ;
Kamiya, S ;
Miwa, T ;
Koga, Y .
GUT, 1997, 41 (01) :49-55
[13]   Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro [J].
Lorca, GL ;
Wadström, T ;
de Valdez, GF ;
Ljungh, Å .
CURRENT MICROBIOLOGY, 2001, 42 (01) :39-44
[14]   Effect of whey-based culture supernatant of Lactobacillus acidophilus (johnsonii) La1 on Helicobacter pylori infection in humans [J].
Michetti, P ;
Dorta, G ;
Wiesel, PH ;
Brassart, D ;
Verdu, E ;
Herranz, M ;
Felley, C ;
Porta, N ;
Rouvet, M ;
Blum, AL ;
Corthésy-Theulaz, I .
DIGESTION, 1999, 60 (03) :203-209
[15]   IN-VITRO INHIBITION OF HELICOBACTER-PYLORI NCTC-11637 BY ORGANIC-ACIDS AND LACTIC-ACID BACTERIA [J].
MIDOLO, PD ;
LAMBERT, JR ;
HULL, R ;
LUO, F ;
GRAYSON, ML .
JOURNAL OF APPLIED BACTERIOLOGY, 1995, 79 (04) :475-479
[16]  
Mrda Z, 1998, Med Pregl, V51, P343
[17]   Functional food science and gastrointestinal physiology and function [J].
Salminen, S ;
Bouley, C ;
Boutron-Ruault, MC ;
Cummings, JH ;
Franck, A ;
Gibson, GR ;
Isolauri, E ;
Moreau, MC ;
Roberfroid, M ;
Rowland, I .
BRITISH JOURNAL OF NUTRITION, 1998, 80 :S147-S171