Differential expression of LIM-homeodomain genes in the embryonic murine brain

被引：21

作者：

Matsumoto, K

Tanaka, T

Furuyama, T

Kashihara, Y

Ishii, N

Tohyama, M

Kitanaka, J

Takemura, M

Mori, T

Wanaka, A

机构：

[1] OSAKA UNIV,CENT LAB,SCH MED,OSAKA 565,JAPAN

[2] OSAKA UNIV,DEPT ANAT & NEUROSCI,SCH MED,OSAKA 565,JAPAN

[3] HYOGO MED UNIV,DEPT PHARMACOL,NISHINOMIYA,HYOGO 663,JAPAN

[4] FUKUSHIMA MED COLL,INST BIOMED SCI,DEPT CELL SCI,FUKUSHIMA 96012,JAPAN

来源：

NEUROSCIENCE LETTERS | 1996年 / 211卷 / 03期

关键词：

LIM-homeodomain gene; L3; LH-2; lim-1; embryonic brain; regional specification;

D O I：

10.1016/0304-3940(96)12749-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Homeobox-containing genes are associated with the control of various stages in embryogenesis. LIM-homeodomain genes have been implicated in the control of differentiation of specific cell types in both neuronal and non-neuronal tissues, yet there have been few studies comparing the expression domains of these genes in the developing brain of a single species, In the present study, we isolated murine LIM-homeodomain genes (LH-2, lim-1, and L3) by reverse transcription-polymerase chain reaction (RT-PCR) method and investigated their expression domains in the embryonic brain by in situ hybridization analysis. These mRNAs showed mutually exclusive expression patterns suggesting that these factors may be involved in region-specific differentiation in the developing brain.

引用

页码：147 / 150

页数：4

共 21 条

[1] APTEROUS IS A DROSOPHILA LIM DOMAIN GENE REQUIRED FOR THE DEVELOPMENT OF A SUBSET OF EMBRYONIC MUSCLES [J].