Highly effective synthesis of 4-halo-tetrahydropyrans via a highly diastereoselective in situ prins-type cyclization reaction

被引：102

作者：

Yang, J ^{[1
]}

Viswanathan, GS ^{[1
]}

Li, CJ ^{[1
]}

机构：

[1] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(99)00027-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of aldehyde with homoallyl alcohols mediated by indium trichloride generated 4-chlorotetrahydropyrans in high yields and,vith high stereoselectivity. The same type of compounds can be generated through a single step, multi-component coupling between aldehyde and allyl bromide mediated by indium (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1627 / 1630

页数：4

共 18 条

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