RNA localization and the development of asymmetry during Drosophila oogenesis

被引：63

作者：

Grunert, S ^{[1
]}

StJohnston, D ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,DEPT GENET,CAMBRIDGE CB2 1QR,ENGLAND

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1996年 / 6卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0959-437X(96)80059-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent work on axis formation in Drosophila has revealed that polarity arises in several distinct stages during oogenesis. One cell of a germline cyst is selected to become the oocyte, the position of the oocyte determines the posterior of the follicle, and the position of the oocyte nucleus determines the dorsal side. Each of these symmetry-breaking steps involves the asymmetric localization of a unique structure, leading to polarization of the cytoskeleton and the localization of specific mRNAs.

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收藏

页码：395 / 402

页数：8

相关论文

共 59 条

[1] NMR SOLUTION STRUCTURE OF A DSRNA BINDING DOMAIN FROM DROSOPHILA STAUFEN PROTEIN REVEALS HOMOLOGY TO THE N-TERMINAL DOMAIN OF RIBOSOMAL-PROTEIN S5 [J].

BYCROFT, M ;

GRUNERT, S ;

MURZIN, AG ;

PROCTOR, M ;

STJOHNSTON, D .

EMBO JOURNAL, 1995, 14 (14) :3563-3571

[2] TRANSIENT POSTERIOR LOCALIZATION OF A KINESIN FUSION PROTEIN REFLECTS ANTEROPOSTERIOR POLARITY OF THE DROSOPHILA OOCYTE [J].

CLARK, I ;

GINIGER, E ;

RUOHOLABAKER, H ;

JAN, LY ;

JAN, YN .

CURRENT BIOLOGY, 1994, 4 (04) :289-300

[3] CAPPUCCINO, A DROSOPHILA MATERNAL EFFECT GENE REQUIRED FOR POLARITY OF THE EGG AND EMBRYO, IS RELATED TO THE VERTEBRATE LIMB DEFORMITY LOCUS [J].

EMMONS, S ;

PHAN, H ;

CALLEY, J ;

CHEN, WL ;

JAMES, B ;

MANSEAU, L .

GENES & DEVELOPMENT, 1995, 9 (20) :2482-2494

[4] OSKAR ORGANIZES THE GERM PLASM AND DIRECTS LOCALIZATION OF THE POSTERIOR DETERMINANT NANOS [J].

EPHRUSSI, A ;

DICKINSON, LK ;

LEHMANN, R .

CELL, 1991, 66 (01) :37-50

[5] INDUCTION OF GERM-CELL FORMATION BY OSKAR [J].

EPHRUSSI, A ;

LEHMANN, R .

NATURE, 1992, 358 (6385) :387-392

[6] REQUIREMENT FOR DROSOPHILA CYTOPLASMIC TROPOMYOSIN IN OSKAR MESSENGER-RNA LOCALIZATION [J].

ERDELYI, M ;

MICHON, AM ;

GUICHET, A ;

GLOTZER, JB ;

EPHRUSSI, A .

NATURE, 1995, 377 (6549) :524-527

[7] STAUFEN PROTEIN ASSOCIATES WITH THE 3'UTR OF BICOID MESSENGER-RNA TO FORM PARTICLES THAT MOVE IN A MICROTUBULE-DEPENDENT MANNER [J].

FERRANDON, D ;

ELPHICK, L ;

NUSSLEINVOLHARD, C ;

STJOHNSTON, D .

CELL, 1994, 79 (07) :1221-1232

[8] MODULATION OF SPECTRIN ACTIN ASSEMBLY BY ERYTHROCYTE ADDUCIN [J].

GARDNER, K ;

BENNETT, V .

NATURE, 1987, 328 (6128) :359-362

[9] Identification of cis-acting sequences that control nanos RNA localization [J].

Gavis, ER ;

Curtis, D ;

Lehmann, R .

DEVELOPMENTAL BIOLOGY, 1996, 176 (01) :36-50

[10] HOMELESS IS REQUIRED FOR RNA LOCALIZATION IN DROSOPHILA OOGENESIS AND ENCODES A NEW MEMBER OF THE DE-H FAMILY OF RNA-DEPENDENT ATPASES [J].

GILLESPIE, DE ;

BERG, CA .

GENES & DEVELOPMENT, 1995, 9 (20) :2495-2508

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