Iron-Catalyzed Regioselective Direct Oxidative Aryl-Aryl Cross-Coupling

被引：67

作者：

Chandrasekharam, Malapaka ^{[1
]}

Chiranjeevi, Barreddi ^{[1
]}

Gupta, Kankatala S. V. ^{[1
]}

Sridhar, B. ^{[2
]}

机构：

[1] Indian Inst Chem Technol, I&PC Div, Hyderabad 500607, Andhra Pradesh, India

[2] Indian Inst Chem Technol, Lab Xray Crystallog, Hyderabad 500607, Andhra Pradesh, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 24期

关键词：

C-H BOND; SUZUKI-MIYAURA; IRON(III) CHLORIDE; N-ARYLATION; ACTIVATION; SP(2); ALKYLATION; REACTIVITY; COMPLEXES; ADJACENT;

D O I：

10.1021/jo202152b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regioselective iron-catalyzed cross-dehydrogenative coupling (CDC) of two aromatic compounds using tert-BuOOH as oxidant under mild conditions has been reported. The direct oxidative coupling reaction is selective toward creation of a carbon-carbon bond at the position ortho to the functional groups of the substrates, completely preventing the homocoupled products. The C-C bond-forming reaction makes the method versatile, leading to functionalized 2,2' -disubstituted biaryls.

引用

页码：10229 / 10235

页数：7

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