Palladium-Catalyzed Cross-Coupling of Polyfluoroarenes with Simple Arenes

被引：171

作者：

Li, Hu ^{[1
,2
,3
]}

Liu, Jia ^{[1
,2
,3
]}

Sun, Chang-Liang ^{[1
,2
,3
]}

Li, Bi-Jie ^{[1
,2
,3
]}

Shi, Zhang-Jie ^{[1
,2
,3
,4
]}

机构：

[1] Peking Univ, Beijing Natl Lab Mol Sci BNLMS, Beijing 100871, Peoples R China

[2] Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Coll Chem, Beijing 100871, Peoples R China

[3] Peking Univ, Green Chem Ctr, Beijing 100871, Peoples R China

[4] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 02期

关键词：

ELECTRON-DEFICIENT POLYFLUOROARENES; C-H FUNCTIONALIZATION; DIRECT ARYLATION; ORGANIC SEMICONDUCTORS; UNACTIVATED ARENES; BOND FORMATION; F BOND; ALKENYLATION; ACTIVATION; PERFLUOROARENES;

D O I：

10.1021/ol102688e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The most efficient method to construct biaryls is the direct dehydrogenative cross-coupling of two different aromatic rings. Such an ideal cross arylation starting from distinct polyfluoroarenes and simple arenes was presented. The selectivity of the cross-coupling was controlled by both of the electronic property of fluoroarenes and steric hindrance of simple arenes. Diisopropyl sulfide was essential to promote the efficacy.

引用

页码：276 / 279

页数：4

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