Copper-catalyzed arylation and alkenylation of polyfluoroarene C-H bonds

被引：382

作者：

Do, Hien-Quang ^{[1
]}

Daugulis, Olafs ^{[1
]}

机构：

[1] Univ Houston, Dept Chem, Houston, TX 77204 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 04期

关键词：

D O I：

10.1021/ja077862l

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient, copper-catalyzed method for the arylation, alkenylation, and benzylation of polyfluoroarenes has been developed. Arenes containing two or more fluorine substituents on the aromatic ring can be efficiently functionalized. The best results are obtained by using a combination of copper iodide catalyst, phenanthroline ligand, aryl bromide or aryl iodide coupling partner, and DMF or DMF/xylene mixed solvent.

引用

页码：1128 / +

页数：3

共 41 条

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