Not just angiogenesis - wider roles for the angiopoietins

被引:56
作者
Jones, PF [1 ]
机构
[1] Univ Leeds, St James Hosp, Mol Med Unit, Leeds LS9 7TF, W Yorkshire, England
关键词
angiopoietins; Tie2; angiogenesis; endothelium;
D O I
10.1002/path.1452
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Since the discovery of the angiopoietins, much interest has been focused on their biological actions and their potential use as therapeutic targets. It is generally accepted that the angiopoietins; play an important role in angiogenesis and hence are described as angiogenic factors. However, it is becoming increasingly clear that this is not their only role and it is likely that the angiopoietins have important roles in a wider range of biological and pathological functions. Copyright (C) 2003 John Wiley Sons, Ltd.
引用
收藏
页码:515 / 527
页数:13
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