Direct evidence for the importance of hydrophobic mismatch for cell membrane recognition

被引：29

作者：

Ghebremariam, B ^{[1
]}

Sidorov, V ^{[1
]}

Matile, S ^{[1
]}

机构：

[1] Georgetown Univ, Dept Chem, Washington, DC 20057 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 08期

关键词：

D O I：

10.1016/S0040-4039(99)00006-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this Letter, we describe the synthesis of amphiphilic oligo(p-phenylene)s from 31 to 44 Angstrom length and delineate the interaction of these rigid-rod molecules with lipid bilayers using fluorescence quenching methods. The results demonstrate high importance of hydrophobic mismatch for selective cell membrane recognition by rigid-rod molecules. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1445 / 1448

页数：4

共 18 条

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