A water-soluble perylene dye functionalised with a 17β-estradiol: a new fluorescent tool for steroid hormones

被引:57
作者
Cespedes-Guirao, Francisco J. [2 ]
Ropero, Ana B. [1 ]
Font-Sanchis, Enrique [2 ]
Nadal, Angel [1 ]
Fernandez-Lazaro, Fernando [2 ]
Sastre-Santos, Angela [2 ]
机构
[1] Univ Miguel Hernandez, Unidad Fisiol Celular & Nutr, Inst Bioingn, Elche 03202, Spain
[2] Univ Miguel Hernandez, Div Quim Organ, Inst Bioingn, Elche 03202, Spain
关键词
MEMBRANE ESTROGEN-RECEPTORS; FIELD-EFFECT TRANSISTORS; SENSITIZED SOLAR-CELLS; ION PAIR STATES; PLASMA-MEMBRANE; ELECTRON-TRANSFER; MAGNESIUM-ION; CHARGE; TRANSPORT; ENERGY;
D O I
10.1039/c1cc10966a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We have successfully been able to synthesise a specific estrogen receptor-directed biolabel based on a fluorescent water-soluble perylenebisimide, thus offering great potential for determining the presence of estrogen receptors in any kind of cell. Moreover, this synthetic strategy allows the preparation of other conjugates involved in the study of any kind of receptor, simply by selecting the appropriate agonist or antagonist.
引用
收藏
页码:8307 / 8309
页数:3
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