Growth factors

被引：7

作者：

Aloisi, F ^{[1
]}

机构：

[1] Ist Super Sanita, Dept Cell Biol & Neurosci, I-00161 Rome, Italy

来源：

NEUROLOGICAL SCIENCES | 2003年 / 24卷 / Suppl 5期

关键词：

multiple sclerosis; remyelination; neuroprotection; growth factors; glial cells;

D O I：

10.1007/s10072-003-0177-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Recent studies have provided new insights on the identity and mechanisms of action of growth factors implicated in myelination processes. Members of several different families of growth factors have been shown to affect oligodendrocyte survival, proliferation and differentiation and their manipulation in the experimental animal provides a means to clarify the molecular mechanisms underlying repair processes in the injured central nervous system. A future challenge is to use this knowledge to boost remyelination and ameliorate clinical symptoms in patients with demyelinating diseases, like multiple sclerosis.

引用

页码：S291 / S294

页数：4

共 16 条

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