Sulphamic acid - A mild, efficient, and cost-effective solid acid catalyst for the synthesis of bis(1H-indol-3-yl)methanes

被引：45

作者：

Singh, PR ^{[1
]}

Singh, DU ^{[1
]}

Samant, SD ^{[1
]}

机构：

[1] Univ Inst Chem Technol, Organ Chem Res Lab, Bombay 400019, Maharashtra, India

来源：

SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 16期

关键词：

aldehydes; bis(indolyl)methane; indoles; ketones; sulphamic acid;

D O I：

10.1080/00397910500180428

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulphamic acid (SA) is found to efficiently catalyze the electrophilic substitution reactions of indoles with aldehydes and ketones in ethanol to afford the corresponding bis(indolyl)methanes. The method is simple and cost effective, and gives good yields in short reaction times. The catalyst is found to be recyclable.

引用

页码：2133 / 2138

页数：6

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