New chiral auxiliaries in enantioselective heterogeneous catalytic hydrogenations:: (-) and (+)-dihydro-apovincaminic acid.: Comparison with (-)-dihydro-apovincaminic acid ethyl ester.: III

被引：26

作者：

Farkas, G

Fodor, K

Tungler, A ^{[1
]}

Máthé, T

Tóth, G

Sheldon, RA

机构：

[1] Tech Univ Budapest, Dept Chem Technol, H-1521 Budapest, Hungary

[2] Hungarian Acad Sci, Organ Chem Technol Res Grp, Budapest, Hungary

[3] Tech Univ Budapest, Dept Gen & Analyt Chem, HAS, Tech Analyt Res Grp, H-1521 Budapest, Hungary

[4] Delft Univ Technol, Lab Organ Chem & Catalysis, NL-2628 BL Delft, Netherlands

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1999年 / 138卷 / 2-3期

基金：

匈牙利科学研究基金会;

关键词：

dihydro-apovincaminic acid; hydrogenation; enantioselectivity; chiral auxiliary; ethyl pyruvate; isophorone;

D O I：

10.1016/S1381-1169(98)00140-X

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The preparation, characterisation, use and comparison with (-)-dihydro-apovincaminic acid ethyl ester of(-) and (+)-dihydro-apovincaminic acid as chiral modifier in heterogeneous catalytic asymmetric hydrogenations are reported. The epimeric compositions were determined using NMR and HPLC methods. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：123 / 127

页数：5

共 8 条

[1]

GEDEON R, Patent No. 4035370

[2] ASYMMETRIC HYDROGENATION WITH MODIFIED RANEY NICKEL .1. STUDIES ON MODIFIED HYDROGENATION CATALYST .2. [J].