Amyloid-β-related angiitis:: a rare cause of recurrent transient neurological symptoms

Background A 79-year-old woman presented with transient right-sided weakness. She subsequently developed further transient neurological signs and symptoms across a range of vascular territories. Diagnostic workup revealed no clear etiology. The patient developed a sudden, fatal intracerebral hemorrhage, and the diagnosis was only revealed at autopsy. Investigations Neurological examination, head CT, brain MRI, fluid-attenuated inversion recovery imaging, magnetic resonance angiography, lumbar puncture, CT angiography, electroencephalography, and brain autopsy. Diagnosis Amyloid-p-related angiitis. Management The patient expired before treatment could be initiated. Immunosuppressants are recommended for future cases.