BioMOFs: Metal-Organic Frameworks for Biological and Medical Applications

被引:1058
作者
McKinlay, Alistair C. [1 ]
Morris, Russell E. [1 ]
Horcajada, Patricia [2 ]
Ferey, Gerard [2 ]
Gref, Ruxandra [3 ,4 ]
Couvreur, Patrick [3 ,4 ]
Serre, Christian [2 ]
机构
[1] Univ St Andrews, EaStChem Sch Chem, St Andrews KY16 9ST, Fife, Scotland
[2] Univ Versailles, Inst Lavoisier, CNRS, UMR 8180, F-78035 Versailles, France
[3] Univ Paris Sud, Fac Pharm, CNRS 8612, F-92296 Chatenay Malabry, France
[4] 3CNRS 2301, F-91190 Gif Sur Yvette, France
关键词
drug delivery; metal-organic frameworks; nitric oxide; theranostics; NITRIC-OXIDE; DRUG-DELIVERY; ADSORPTION; STORAGE; HYDROGEN; PLATFORM; RELEASE; DONORS; NO;
D O I
10.1002/anie.201000048
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
New packaging: A tremendous number of drugs have been developed but not applied further owing to poor bioavailability. To solve this problem, stable nontoxic metal-organic frameworks have been developed as drug-delivery vehicles and even as bioactive species in their own right. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:6260 / 6266
页数:7
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