Use of nanomaterials for impedimetric DNA sensors: A review

被引:142
作者
Bonanni, A. [1 ,2 ]
del Valle, M. [1 ]
机构
[1] Univ Autonoma Barcelona, Dept Chem, Sensors & Biosensors Grp, E-08193 Barcelona, Spain
[2] Natl Inst Mat Sci, Int Ctr Mat Nanoarchitecton MANA, Ctr Biomat, Tsukuba, Ibaraki, Japan
关键词
Biosensor; Genosensor; Carbon nanotube; Gold nanoparticles; Quantum dots; Electrochemical impedance spectroscopy; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; SURFACE-PLASMON RESONANCE; WALLED CARBON NANOTUBES; LABEL-FREE DETECTION; HYBRIDIZATION DETECTION; ELECTRICAL DETECTION; ELECTRONIC TRANSDUCTION; PAT GENE; BIOMOLECULAR INTERACTIONS; IMMOBILIZATION METHOD;
D O I
10.1016/j.aca.2010.08.022
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This review presents the state of the art of DNA sensors (or genosensors) that utilize electrochemical impedance spectroscopy as the transduction technique. As issue of current interest, it is centered on the use of nanomaterials to develop or to improve performance of these specific biosensors. It will describe the different principles that may be employed in the measuring step and the different formats adopted for detection of a DNA sequence or confirmation or amplification of the finally obtained signal. The use of nanomaterials for the above listed aspects, viz, the use of carbon nanotubes or other nanoscopic elements in the construction of the electrodes, or the use of nanoparticles, mainly gold or quantum dots, for signal enhancement will be fully revised. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:7 / 17
页数:11
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