Islet transplantation: Present clinical situation and future aspects

被引：20

作者：

Bretzel, RG

Brendel, M

Eckhard, M

Brandhorst, D

Jaeger, C

Hatziagelaki, E

Federlin, K

机构：

[1] Univ Giessen, Dept Med 3, Giessen, Germany

[2] Univ Giessen, Policlin, Giessen, Germany

来源：

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES | 2001年 / 109卷

关键词：

islet transplantation; kidney transplantation; end-stage renal disease; alloimmunity; autoimmunity; immunosuppression; immunotolerance; gene therapy;

D O I：

10.1055/s-2001-18597

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Beta-cell replacement either by pancreatic organ or islet cell transplantation is the only treatment to achieve an insulin-independent, normoglycemic state and to avoid hypoglycemic episodes in patients with type 1 diabetes mellitus, This article will review the state-of-the-art in clinical islet cell personal experience. transplantation at the dawn of the new millenium and will provide an outlook on the basis of extended personal experience.

引用

页码：S384 / S399

页数：16

共 65 条

[11] Assessment of intracellular insulin content during all steps of human islet isolation procedure [J].