Stereoselective additions of grignard reagents to masked imines and iminium ions

被引：12

作者：

Bortolussi, M ^{[1
]}

Cinquin, C ^{[1
]}

Bloch, R ^{[1
]}

机构：

[1] UNIV PARIS 11,INST CHIM MOL ORSAY,LAB CARBOCYCLES,F-91405 ORSAY,FRANCE

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(96)02013-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Additions of organomagnesium bromides to the masked imine 2 or iminium ion 3 were found to be highly diastereoselective, and were shown to occur on the same diastereotopic face of the C=N bonds of these two compounds. Thermolysis of the aminoalcohols obtained gave rise to chiral allylic aminoalcohols of high synthetic potential. Copyright (C) 1996 Published by Elsevier Science Ltd

引用

页码：8729 / 8732

页数：4

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