Enhanced vector competence of Aedes aegypti (Diptera:Culicidae) from the torres strait compared with mainland Australia for dengue 2 and 4 viruses

被引:44
作者
Knox, TB [1 ]
Kay, BH
Hall, RA
Ryan, PA
机构
[1] Queensland Inst Med Res, Herston, Qld 4029, Australia
[2] Univ Queensland, Australian Ctr Int & Trop Hlth & Nutr, PO Royal Brisbane Hosp, Herston, Qld 4029, Australia
[3] Univ Queensland, Sch Mol & Microbial Sci, Dept Microbiol & Parasitol, St Lucia, Qld 4027, Australia
关键词
Aedes aegypti; dengue; vector competence; virus; transmission;
D O I
10.1603/0022-2585-40.6.950
中图分类号
Q96 [昆虫学];
学科分类号
摘要
Australian Aedes aegypti (L.) mosquitoes colonized from the Torres Strait and three mainland localities (Charters Towers, Townsville, and Cairns) were fed on blood suspensions containing dengue virus type 2 (DEN-2) or dengue virus type 4 (DEN-4). Variation was found in oral susceptibility to DEN-2 (59-99% infection) and DEN-4 (28-79% infection) among Ae. aegypti assayed for virus at 8, 12, 16, or 20 d after ingestion of infected blood. Torres Strait Ae. aegypti were the most susceptible to DEN-2 and were significantly more efficient in transmission to capillary tube at 16 d (76% transmission) than mainland Ae. aegypti populations (20-28% transmission). Torres Strait Ae. aegypti were also the most susceptible to DEN-4, although transmission did not vary significantly from mainland populations at 16 d (12% compared with 0-4%) or 20 d (16% compared with 4-16%). Disseminated infection (i.e., leg infection) with either DEN-2 or DEN-4 was not an accurate predictor of transmission potential. This study demonstrates differences among Australian Ae. aegypti populations in vector competence for DEN-2 and DEN-4. Torres Strait Ae. aegypti were more frequently infected and able to transmit DEN-2 at higher rates than mainland populations. These data indicate that the Torres Strait region is potentially more receptive to dengue transmission than mainland localities, a finding discussed with respect to past outbreaks.
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收藏
页码:950 / 956
页数:7
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