Assembling polycyclic bisguanidine motifs resembling batzelladine alkaloids by double tethered biginelli condensations

被引：20

作者：

Cohen, F ^{[1
]}

Collins, SK ^{[1
]}

Overman, LE ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 23期

关键词：

D O I：

10.1021/ol0357999

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Double tethered Biginelli condensations furnish linked polycyclic bisguanidines or bisureas. Alteration of the bis-beta-ketoester component allows bispolycyclic guanidine motifs to be constructed that resemble natural batzelladine alkaloids or have novel linkages.

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页码：4485 / 4488

页数：4

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