How might cohesin hold sister chromatids together?

被引:74
作者
Nasmyth, K [1 ]
机构
[1] IMP, Res Inst Mol Pathol, A-1030 Vienna, Austria
关键词
sister chromatid cohesion; cohesin; SMC and Kleisin proteins; chromosome segregation; mitosis; meiosis;
D O I
10.1098/rstb.2004.1604
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The sister chromatid cohesion essential for the bi-orientation of chromosomes on mitotic spindles depends on a multi-subunit complex called cohesin. This paper reviews the evidence that cohesin is directly responsible for holding sister DNAs together and considers how it might perform this function in the light of recent data on its structure.
引用
收藏
页码:483 / 496
页数:14
相关论文
共 79 条
[51]   From a single double helix to paired double helices and back [J].
Nasmyth, K ;
Schleiffer, A .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2004, 359 (1441) :99-108
[52]   Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast [J].
Nonaka, N ;
Kitajima, T ;
Yokobayashi, S ;
Xiao, GP ;
Yamamoto, M ;
Grewal, SIS ;
Watanabe, Y .
NATURE CELL BIOLOGY, 2002, 4 (01) :89-93
[53]   Pds5 cooperates with cohesin in maintaining sister chromatid cohesion [J].
Panizza, S ;
Tanaka, TU ;
Hochwagen, A ;
Eisenhaber, F ;
Nasmyth, K .
CURRENT BIOLOGY, 2000, 10 (24) :1557-1564
[54]   A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction [J].
Pasierbek, P ;
Jantsch, M ;
Melcher, M ;
Schleiffer, A ;
Schweizer, D ;
Loidl, J .
GENES & DEVELOPMENT, 2001, 15 (11) :1349-1360
[55]   Un menage a quatre: The molecular biology of chromosome segregation in meiosis [J].
Petronczki, M ;
Siomos, MF ;
Nasmyth, K .
CELL, 2003, 112 (04) :423-440
[56]   Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II [J].
Rabitsch, KP ;
Gregan, J ;
Schleiffer, A ;
Javerzat, JP ;
Eisenhaber, F ;
Nasmyth, K .
CURRENT BIOLOGY, 2004, 14 (04) :287-301
[57]   Cohesin SMC1β is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination [J].
Revenkova, E ;
Eijpe, M ;
Heyting, C ;
Hodges, CA ;
Hunt, PA ;
Liebe, B ;
Scherthan, H ;
Jessberger, R .
NATURE CELL BIOLOGY, 2004, 6 (06) :555-562
[58]   Novel meiosis-specific isoform of mammalian SMC1 [J].
Revenkova, E ;
Eijpe, M ;
Heyting, C ;
Gross, B ;
Jessberger, R .
MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (20) :6984-6998
[59]  
Rieder CL, 1999, J CELL SCI, V112, P2607
[60]   Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis [J].
Salic, A ;
Waters, JC ;
Mitchison, TJ .
CELL, 2004, 118 (05) :567-578