Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A

被引：67

作者：

Carr, Gavin ^{[2
]}

Chung, Marco K. W. ^{[1
]}

Mauk, A. Grant ^{[1
]}

Andersen, Raymond J. ^{[2
]}

机构：

[1] Univ British Columbia, Dept Biochem & Mol Biol, Vancouver, BC V6T 1Z3, Canada

[2] Univ British Columbia, Dept Chem & Earth Ocean Sci, Vancouver, BC V6T 1Z1, Canada

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2008年 / 51卷 / 09期

关键词：

D O I：

10.1021/jm800143h

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.

引用

页码：2634 / 2637

页数：4

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