Modes of Transmission of Zika Virus

被引：96

作者：

Gregory, Christopher J. ^{[1
]}

Oduyebo, Titilope ^{[2
]}

Brault, Aaron C. ^{[1
]}

Brooks, John T. ^{[3
]}

Chung, Koo-Whang ^{[4
]}

Hills, Susan ^{[1
]}

Kuehnert, Matthew J. ^{[4
]}

Mead, Paul ^{[1
]}

Meaney-Delman, Dana ^{[5
]}

Rabe, Ingrid ^{[1
]}

Staples, Erin ^{[1
]}

Petersen, Lyle R. ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Div Vector Borne Dis, 3156 Rampart Rd, Ft Collins, CO 80521 USA

[2] Ctr Dis Control & Prevent, Div Reprod Hlth, Atlanta, GA USA

[3] Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USA

[4] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA USA

[5] Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2017年 / 216卷

基金：

美国国家卫生研究院;

关键词：

Zika virus; transmission modes; Aedes mosquitoes; pathogenesis; WEST-NILE-VIRUS; MALE SEXUAL TRANSMISSION; AEDES-AEGYPTI; PLACENTAL TROPHOBLASTS; VERTICAL TRANSMISSION; UNITED-STATES; YELLOW-FEVER; PUERTO-RICO; INFECTION; DENGUE;

D O I：

10.1093/infdis/jix396

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

For > 60 years, Zika virus (ZIKV) has been recognized as an arthropod-borne virus with Aedes species mosquitoes as the primary vector. However in the past 10 years, multiple alternative routes of ZIKV transmission have been identified. We review the available data on vector and non-vector-borne modes of transmission and interventions undertaken, to date, to reduce the risk of human infection through these routes. Although much has been learned during the outbreak in the Americas on the underlying mechanisms and pathogenesis of non-vector-borne ZIKV infections, significant gaps remain in our understanding of the relative incidence of, and risk from, these modes compared to mosquito transmission. Additional research is urgently needed on the risk, pathogenesis, and effectiveness of measures to mitigate non-vector-borne ZIKV transmission.

引用

页码：S875 / S883

页数：9

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