CCancer: a bird's eye view on gene lists reported in cancer- related studies

被引:25
作者
Dietmann, Sabine [2 ]
Lee, Wanseon [1 ]
Wong, Philip [1 ]
Rodchenkov, Igor [3 ]
Antonov, Alexey V. [1 ]
机构
[1] German Res Ctr Environm Hlth GmbH, Helmholtz Ctr Munich, Inst Bioinformat & Syst Biol, D-85764 Neuherberg, Germany
[2] Univ Freiburg, Freiburg Ctr Data Anal & Modeling, D-79104 Freiburg, Germany
[3] Univ Toronto, Fac Med, BBDMR, CCBR, Toronto, ON, Canada
关键词
EXPRESSION; DATABASE; CONTEXT; TOOL;
D O I
10.1093/nar/gkq515
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
CCancer is an automatically collected database of gene lists, which were reported mostly by experimental studies in various biological and clinical contexts. At the moment, the database covers 3369 gene lists extracted from 2644 papers published in similar to 80 peer-reviewed journals. As input, CCancer accepts a gene list. An enrichment analyses is implemented to generate, as output, a highly informative survey over recently published studies that report gene lists, which significantly intersect with the query gene list. A report on gene pairs from the input list which were frequently reported together by other biological studies is also provided. CCancer is freely available at http://mips.helmholtz-muenchen.de/proj/ccancer.
引用
收藏
页码:W118 / W123
页数:6
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