GeneSet2miRNA: finding the signature of cooperative miRNA activities in the gene lists

被引：37

作者：

Antonov, Alexey V. ^{[1
]}

Dietmann, Sabine ^{[1
]}

Wong, Philip ^{[1
]}

Lutter, Dominik ^{[1
]}

Mewes, Hans W. ^{[1
,2
]}

机构：

[1] Inst Bioinformat & Syst Biol, German Res Ctr Environm Hlth GmbH, Helmholtz Zentrum Munchen, D-85764 Neuherberg, Germany

[2] Tech Univ Munich, Dept Genome Oriented Bioinformat, Wissensch Zentrum Weihenstephan, D-85350 Freising Weihenstephan, Germany

来源：

NUCLEIC ACIDS RESEARCH | 2009年 / 37卷

关键词：

COMPLEX FUNCTIONALITY; DATABASE RESOURCES; NATIONAL-CENTER; WEB TOOL; MICRORNA; EXPRESSION; ANNOTATION; PATHWAYS; GENOMICS; KEGG;

D O I：

10.1093/nar/gkp313

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

GeneSet2miRNA is the first web-based tool which is able to identify whether or not a gene list has a signature of miRNA-regulatory activity. As input, GeneSet2miRNA accepts a list of genes. As output, a list of miRNA-regulatory models is provided. A miRNA-regulatory model is a group of miRNAs (single, pair, triplet or quadruplet) that is predicted to regulate a significant subset of genes from the submitted list. GeneSet2miRNA provides a user friendly dialog-driven web page submission available for several model organisms. GeneSet2miRNA is freely available at http://mips.helmholtz-muenchen.de/proj/gene2mir/.

引用

收藏

页码：W323 / W328

页数：6

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