Biosynthesis of isoprenoids in Escherichia coli:: Retention of the methyl H-atoms of 1-deoxy-D-xylulose

被引：18

作者：

Giner, JL ^{[1
]}

Jaun, B

机构：

[1] SUNY Syracuse, ESF, Dept Chem, Syracuse, NY 13210 USA

[2] Swiss Fed Inst Technol, Organ Chem Lab, CH-8092 Zurich, Switzerland

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 44期

关键词：

biosynthesis; isoprenoids; labeling; vitamins;

D O I：

10.1016/S0040-4039(98)01791-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Investigation of isoprenoid biosynthesis in E. coli using [1,1,1-H-2(3)]-1-deoxy-D-xylulose shows the methyl group of 1-deoxyxylulose to be incorporated into the methyl groups of ubiquinone originating from the methyl group of IPP and the (Z)-methyl group of DMAPP, and that this incorporation involves nd loss of methyl hydrogen atoms. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：8021 / 8022

页数：2

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