Compliance as a critical consideration in patients who appear to be resistant to aspirin after healing of myocardial infarction

被引：184

作者：

Schwartz, KA

Schwartz, DE

Ghosheh, K

Reeves, MJ

Barber, K

DeFranco, A

机构：

[1] Michigan State Univ, Dept Med, E Lansing, MI 48824 USA

[2] Michigan State Univ, Dept Epidemiol, E Lansing, MI 48824 USA

[3] McLaren Med Ctr, Dept Res, Flint, MI USA

[4] McLaren Med Ctr, Dept Cardiol, Flint, MI USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2005年 / 95卷 / 08期

关键词：

D O I：

10.1016/j.amjcard.2004.12.038

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The hypothesis that aspirin resistance is often due to noncompliance was investigated. One hundred ninety patients with a history of myocardial infarction were evaluated using arachiclonic acid-stimulated, light aggregometry at 3 different time points: while receiving their usual daily aspirin, after not receiving aspirin for 7 days, and 2 hours after the observed ingestion of aspirin 325 mg. At the first time point, 17 patients (9%) failed to show aspirin inhibitibon of platelet aggregation, but 2 hours after observed aspirin ingestion, aspirin inhibition was observed in all but 1 patient. (c) 2005 by Excerpta Medica Inc.

引用

收藏

页码：973 / 975

页数：3

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