Facile Catalytic Hydrosilylation of Pyridines

被引：140

作者：

Gutsulyak, Dmitry V. ^{[1
]}

van der Est, Art ^{[1
]}

Nikonov, Georgii I. ^{[1
]}

机构：

[1] Brock Univ, Dept Chem, 500 Glenridge Ave, St Catharines, ON L2S 3A1, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 06期

基金：

加拿大自然科学与工程研究理事会;

关键词：

chemoselectivity; heterocycles; hydrosilylation; ruthenium; zinc; ONE-POT CONVERSION; IRON-SILICON BOND; ASYMMETRIC HYDROSILYLATION; TRANSFER HYDROGENATION; ENANTIOSELECTIVE HYDROSILYLATION; TERTIARY-AMINES; NITRO-COMPOUNDS; REDUCTION; IMINES; AMIDES;

D O I：

10.1002/anie.201006135

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Not only surprisingly facile, a hydrosilylation of pyridines under the catalysis of [Cp(iPr3P)Ru(NCCH3)2]+ has the advantages that it is 1,4-regioselective and reversible. The products can be transformed in a variety of ways (see scheme). The related complex [CpRu(NCCH3)3]+ catalyzes the two-hydrogen-atom reduction of phenanthroline by HSiMe2Ph/water. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1384 / 1387

页数：4

共 92 条

[1]

ANDRIANOV KA, 1977, ZH OBSHCH KHIM+, V47, P485

[2] HYDROSILYLATION OF AROMATIC AZOMETHINS .1. INTERCONVERSION OF FINAL AND INTERMEDIATE COMPOUNDS IN PROCESS OF CATALYTIC REACTION OF TRIALKYL-HYDROSILANES OR ARYL-HYDROSILANES WITH BENZYLIDENE ANILINE [J].

ANDRIANOV, KA ;

FILIMONOVA, MI ;

SIDOROV, VI .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1977, 142 (01) :31-37

[3]

[Anonymous], ANGEW CHEM

[4]

[Anonymous], 1992, COMPREHENSIVE HDB HY, DOI DOI 10.1016/C2009-0-11185-6

[5]

[Anonymous], 1998, ANGEW CHEM, V110, P3314

[6] Highly chemoselective metal-free reduction of tertiary amides [J].

Barbe, Guillaume ;

Charette, Andr B. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (01) :18-+

[7] ASYMMETRIC CATALYZES .28. ENANTIOSELECTIVE HYDROSILYLATION OF PROCHIRAL 3,4-DIHYDRO-2H-PYRROLE DERIVATIVES [J].

BECKER, R ;

BRUNNER, H ;

MAHBOOBI, S ;

WIEGREBE, W .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1985, 24 (11) :995-996

[8]

BECKER R, 1985, ANGEW CHEM, V97, P969

[9]

Bower, 1996, ANGEW CHEM, V108, P1662

[10] A mild general procedure for the one-pot conversion of amides to aldehydes [J].

Bower, S ;

Kreutzer, KA ;

Buchwald, SL .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (13-14) :1515-1516

← 1 2 3 4 5 6 7 8 9 10 →