Highly Fluorescent Silica-Coated Bismuth-Doped Aluminosilicate Nanoparticles for Near-Infrared Bioimaging

被引:59
作者
Sun, Hong-Tao [1 ]
Yang, Junjie [2 ,3 ]
Fujii, Minoru [4 ]
Sakka, Yoshio [5 ]
Zhu, Yufang [1 ]
Asahara, Takayuki [2 ]
Shirahata, Naoto [5 ]
Ii, Masaaki [2 ]
Bai, Zhenhua [4 ]
Li, Ji-Guang [5 ]
Gao, Hong [1 ]
机构
[1] Natl Inst Mat Sci, ICYS, Tsukuba, Ibaraki 305047, Japan
[2] RIKEN, Ctr Dev Biol, Inst Biomed Res & Innovat, Kobe, Hyogo 6500047, Japan
[3] Osaka Univ, Grad Sch Med, Dept Surg, Div Cardiovasc Surg, Suita, Osaka 5650871, Japan
[4] Kobe Univ, Dept Elect & Elect Engn, Kobe, Hyogo 6578501, Japan
[5] Natl Inst Mat Sci, Nano Ceram Ctr, Tsukuba, Ibaraki 3050047, Japan
关键词
QUANTUM DOTS; PHOTOLUMINESCENCE; MICROSCOPY; ZEOLITES; SPHERES;
D O I
10.1002/smll.201001011
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The combined advantages of bismuth and aluminosilicates lead to a new type of nanosized biolabel. The near-infrared (NIR)-emitting silica-coated bismuth-doped aluminosilicate nanoparticles are simple to prepare and exhibit a broad excitation band in the first biological window, efficient long-lived photoluminescence (PL) covering the second window, high photostability, low cytotoxicity, and easy penetration into living tissues. In vivo PL bioimaging and decay are tested in living mice. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:199 / 203
页数:5
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