Synthesis and resolution of 1,1-bi-8-methylisoquinoline: Formation of an optically active complex with high chiral recognition

被引：38

作者：

Chelucci, G

Cabras, MA

Saba, A

Sechi, A

机构：

[1] Dipartimento di Chimica, Università di Sassari, I-07100 Sassari

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 04期

关键词：

D O I：

10.1016/0957-4166(96)00107-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis and resolution of 1,1-bi-8-methylisoquinoline (+/-)-5 is reported. An optically active palladium complex with high chiral recognition was formed during the complexation between a chiral palladium complex and the two enantiomers of(+/-)-5. The free energy barrier Delta G(not equal) for interconversion of enantiomers was estimated to be 97,2 KJ/mol at 40 degrees C. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：1027 / 1032

页数：6

共 16 条

[11] RESOLUTIONS USING METAL-COMPLEXES - SYNTHESIS, SEPARATION INTO DIASTEREOISOMERS, AND RESOLUTION OF ORTHO-PHENYLENEBIS(METHYLPHENYLPHOSPHINE) USING PALLADIUM COMPLEXES CONTAINING OPTICALLY-ACTIVE ORTHO-METALLATED DIMETHYL(ALPHA-METHYLBENZYL)AMINES [J].