SMART: The MicroStent's ability to limit restenosis trial

被引:13
作者
Heuser, R
Lopez, A
Kuntz, R
Reduto, L
Badger, R
Coleman, P
Whitlow, P
Iannone, LA
Safian, R
Yeung, A
Moses, J
机构
[1] St Lukes Med Ctr, Phoenix Heart Ctr, Phoenix, AZ 85016 USA
[2] Beth Israel Hosp, Boston, MA USA
[3] St Francis Hosp, Roslyn, NY USA
[4] Utah Valley Cardiol, Provo, UT USA
[5] No Calif Med Assoc, Santa Rosa, CA USA
[6] Cleveland Clin, Cleveland, OH 44106 USA
[7] Mercy Med Ctr, Des Moines, IA USA
[8] William Beaumont Hosp, Royal Oak, MI 48072 USA
[9] Stanford Univ, Ctr Med, Stanford, CA 94305 USA
[10] Lenox Hill Hosp, New York, NY 10021 USA
关键词
coronary artery disease; vessels; coronary stents; revascularization; restenosis;
D O I
10.1002/ccd.1063
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this randomized, prospective, multicenter trial (n = 661) of patients with de novo or restenotic coronary lesions, 330 patients received the MicroStent(R) II (MSII), and 331 received the Palmaz-Schatz(R) (PS) stent. The short-term procedural success rates were 94.4% and 95.7%, respectively (P = 0.47). The 30-day cumulative incidence of major adverse events [death, myocardial infarction, CVA, target lesion revascularization (TLR)] was 6.4% for the MSII and 4.5% for the PS stent (P = 0.31). The in-stent binary restenosis rate at 6 months was 25.2% for the MSII and 22.1% for the PS stent (P = 0.636). Using Kaplan-Meier estimates, the incidence of clinically driven TLR was 8.9% for the MSII and 9.2% for the PS stent at 180 days; at 270 days, it was 12.8% and 12.1%, respectively (P = 0.83). MSII and the PS stents were comparable with respect to short-term procedural success, complications, and late clinical and angiographic restenosis. (C) 2001 Wiley-Liss, Inc.
引用
收藏
页码:269 / 277
页数:9
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