Analysis of antibiotics by capillary electrophoresis

被引:35
作者
Flurer, CL [1 ]
机构
[1] US FDA, Forens Chem Ctr, Cincinnati, OH USA
关键词
antibiotics; capillary electrophoresis; review;
D O I
10.1002/elps.200305639
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Recent developments in the characterization of antibiotics are reviewed. Many capillary electrophoretic techniques have been utilized in their analyses, addressing various aspects of quantifying, profiling, and monitoring. Laser-induced fluorescence detection systems demonstrated their usefulness in clinical settings and in the monitoring of residue levels in food matrices. Different sample introduction methods have been explored, enhancing detection sensitivity, or reducing or eliminating sample manipulation prior to injection.
引用
收藏
页码:4116 / 4127
页数:12
相关论文
共 57 条
  • [1] Determination of drug residues in water by the combination of liquid chromatography or capillary electrophoresis with electrospray mass spectrometry
    Ahrer, W
    Scherwenk, E
    Buchberger, W
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2001, 910 (01) : 69 - 78
  • [2] Detection of doxorubicin and metabolites in cell extracts and in single cells by capillary electrophoresis with laser-induced fluorescence detection
    Anderson, AB
    Gergen, J
    Arriaga, EA
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2002, 769 (01): : 97 - 106
  • [3] Quantitation of the enantiomers of ofloxacin by capillary electrophoresis in the parts per billion concentration range for in vitro drug absorption studies
    Awadallah, B
    Schmidt, PC
    Wahl, MA
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2003, 988 (01) : 135 - 143
  • [4] Simultaneous determination of flumequine and oxolinic acid in chicken tissues by solid phase extraction and capillary electrophoresis
    Barrón, D
    Jiménez-Lozano, E
    Bailac, S
    Barbosa, J
    [J]. ANALYTICA CHIMICA ACTA, 2003, 477 (01) : 21 - 27
  • [5] Determination of difloxacin and sarafloxacin in chicken muscle using solid-phase extraction and capillary electrophoresis
    Barrón, D
    Jiménez-Lozano, E
    Bailac, S
    Barbosa, J
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2002, 767 (02): : 313 - 319
  • [6] Determination of residues of enrofloxacin and its metabolite ciprofloxacin in biological materials by capillary electrophoresis
    Barrón, D
    Jiménez-Lozano, E
    Cano, J
    Barbosa, J
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2001, 759 (01): : 73 - 79
  • [7] Fast analysis of antibacterial isothiazolones by capillary electrophoresis
    Barták, P
    Bednár, P
    Friedecky, D
    Haviger, A
    Sevcík, J
    [J]. JOURNAL OF CHROMATOGRAPHY B, 2001, 758 (02): : 323 - 325
  • [8] de Boer T, 2001, ELECTROPHORESIS, V22, P1413, DOI 10.1002/1522-2683(200105)22:7<1413::AID-ELPS1413>3.0.CO
  • [9] 2-U
  • [10] Analysis of clindamycin by micellar electrokinetic chromatography with a mixed micellar system
    Dehouck, P
    Van Schepdael, A
    Roets, E
    Hoogmartens, J
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2001, 932 (1-2) : 145 - 152