Silica sol-gel monolithic materials and their use in a variety of applications

被引:95
作者
Kato, M
Sakai-Kato, K
Toyo'oka, T
机构
[1] Univ Shizuoka, Sch Pharmaceut Sci, Dept Analyt Chem, Shizuoka 4228526, Japan
[2] Univ Shizuoka, COE Program 21st Century, Shizuoka 4228526, Japan
[3] Musashino Univ, Res Inst Pharmaceut Sci, Tokyo, Japan
关键词
silica sol-gel; analytical chemistry; biomolecule; monolith; high-througput screening;
D O I
10.1002/jssc.200500225
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Sol-gel technology was first discovered in the late 1800s, but it was not until the early 1970s that renewed interest in the technique was generated, when monolithic inorganic gels were formed at low temperature. In this review, we introduce the sol-gel reaction and the properties of the gel matrix in the first half and the applications of the matrix in the latter half.
引用
收藏
页码:1893 / 1908
页数:16
相关论文
共 146 条
[1]   Capillary electrochromatography with monolithic silica columns III. Preparation of hydrophilic silica monoliths having surface-bound cyano groups: chromatographic characterization and application to the separation of carbohydrates, nucleosides, nucleic acid bases and other neutral polar species [J].
Allen, D ;
El Rassi, Z .
JOURNAL OF CHROMATOGRAPHY A, 2004, 1029 (1-2) :239-247
[2]   Capillary electrochromatography with monolithic-silica columns. II. Preparation of amphiphilic silica monoliths having surface-bound cationic octadecyl moieties and their chromatographic characterization and application to the separation of proteins and other neutral and charged species [J].
Allen, D ;
El Rassi, Z .
ANALYST, 2003, 128 (10) :1249-1256
[3]   Entrapment of highly active membrane-bound receptors in macroporous sol-gel derived silica [J].
Besanger, TR ;
Easwaramoorthy, B ;
Brennan, JD .
ANALYTICAL CHEMISTRY, 2004, 76 (21) :6470-6475
[4]   Screening of inhibitors using enzymes entrapped in sol-gel-derived materials [J].
Besanger, TR ;
Chen, Y ;
Deisingh, AK ;
Hodgson, R ;
Jin, W ;
Mayer, S ;
Brook, MA ;
Brennan, JD .
ANALYTICAL CHEMISTRY, 2003, 75 (10) :2382-2391
[5]   Aqueous sol-gel process for protein encapsulation [J].
Bhatia, RB ;
Brinker, CJ ;
Gupta, AK ;
Singh, AK .
CHEMISTRY OF MATERIALS, 2000, 12 (08) :2434-2441
[6]   BIOCHEMICALLY ACTIVE SOL-GEL GLASSES - THE TRAPPING OF ENZYMES [J].
BRAUN, S ;
RAPPOPORT, S ;
ZUSMAN, R ;
AVNIR, D ;
OTTOLENGHI, M .
MATERIALS LETTERS, 1990, 10 (1-2) :1-5
[7]  
Brinker C.J., 1990, SOL GEL SCI
[8]   Sol-gel matrixes doped with atrazine antibodies: Atrazine binding properties [J].
Bronshtein, A ;
Aharonson, N ;
Avnir, D ;
Turniansky, A ;
Altstein, M .
CHEMISTRY OF MATERIALS, 1997, 9 (11) :2632-2639
[9]   Sugar-modified silanes: precursors for silica monoliths [J].
Brook, MA ;
Chen, Y ;
Guo, K ;
Zhang, Z ;
Brennan, JD .
JOURNAL OF MATERIALS CHEMISTRY, 2004, 14 (09) :1469-1479
[10]   Applications of silica-based monolithic HPLC columns [J].
Cabrera, K .
JOURNAL OF SEPARATION SCIENCE, 2004, 27 (10-11) :843-852