Biotransformation of artemisinic acid by cultured cells of Artemisia annua

被引:16
作者
Kawamoto, H
Asada, Y
Sekine, H
Furuya, T
机构
[1] Noda Inst Sci Res, Noda, Chiba 2780037, Japan
[2] Kitasato Univ, Sch Pharmaceut Sci, Minato Ku, Tokyo 108, Japan
[3] Okayama Univ Sci, Fac Sci, Okayama 700, Japan
关键词
Artemisia annua; Compositae; cell culture; biotransformation; sesquiterpene; cadinane; artemisinic acid; artemisinic acid beta-D-glucopyranosyl ester; 9-beta-hydroxyartemisinic acid beta-D-glucopyranosyl ester; 3-beta-hydroxyartemisinic acid beta-D-glucopyranosyl;
D O I
10.1016/S0031-9422(97)01138-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three new biotransformation products, artemisinic acid beta-D-glucopyranosyl ester, 9-beta-hydroxyartemisinic acid beta-D-glucopyranosyl ester and 3-beta-hydroxyartemisinic acid beta-D-glucopyranosyl ester, were isolated from a cell culture of Artemisia annua following the administration of artemisinic acid. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1329 / 1333
页数:5
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