A nucleoside conjugate containing a metallacarborane group and its incorporation into a DNA oligonucleotide

被引：69

作者：

Olejniczak, AB

Plesek, J

Kriz, O

Lesnikowski, ZJ

机构：

[1] Polish Acad Sci, Lab Mol Virol & Biol Chem, Ctr Microbiol & Virol, PL-93232 Lodz, Poland

[2] Acad Sci Czech Republ, Inst Inorgan Chem, CZ-25068 Rez, Czech Republic

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 46期

关键词：

DNA; metallacarboranes; molecular probes; nucleosides; redox chemistry;

D O I：

10.1002/anie.200352505

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nucleoside-metallacarborane conjugates (for example, TBEMC; see picture with low toxicity were synthesized and coupled as a redox label to DNA oligonucleotide. The labeled oligonucleotide acted as a primer for Taq polymerase.

引用

页码：5740 / 5743

页数：4

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