Optimized pH-responsive cyanine fluorochromes for detection of acidic environments

被引：69

作者：

Hilderbrand, Scott A. ^{[1
]}

Weissleder, Ralph ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Ctr Mol Imaging Res, Massachusetts Gen Hosp, Charlestown, MA 02129 USA

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 26期

关键词：

D O I：

10.1039/b703764c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Modulation of pH-responsive cyanine dye pK(a) values via heteroatom substitution allows for design of fluorescent reporters that are tuned for potential imaging of biologically relevant acidic environments.

引用

页码：2747 / 2749

页数：3

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