Rhopaladins A∼D, new indole alkaloids from marine tunicate Rhopalaea sp.

被引：87

作者：

Sato, H

Tsuda, M

Watanabe, K ^{[1
]}

Kobayashi, J

机构：

[1] Hokkaido Univ, Fac Agr, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

[2] Hokkaido Univ, Fac Agr, GC MS, Sapporo, Hokkaido 0600812, Japan

[3] Hokkaido Univ, Fac Agr, NMR, Sapporo, Hokkaido 0600812, Japan

来源：

TETRAHEDRON | 1998年 / 54卷 / 30期

关键词：

D O I：

10.1016/S0040-4020(98)00470-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four new bis(indole) alkaloids, rhopaladins A similar to D (1 similar to 4), have been isolated from the Okinawan marine tunicate Rhopalaea sp. and the structures were elucidated on the basis of spectroscopic data. The presence of two rotational isomers (3a and 3b) of 3 was deduced from NOESY data and molecular calculation using Macromodel program. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：8687 / 8690

页数：4

相关论文

共 16 条

[1] DESIGN AND PERFORMANCE OF A NOVEL ELECTROSPRAY INTERFACE [J].

ALLEN, MH ;

VESTAL, ML .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1992, 3 (01) :18-26

[2] TOPSENTINS, NEW TOXIC BIS-INDOLE ALKALOIDS FROM THE MARINE SPONGE TOPSENTIA-GENITRIX [J].

BARTIK, K ;

BRAEKMAN, JC ;

DALOZE, D ;

STOLLER, C ;

HUYSECOM, J ;

VANDEVYVER, G ;

OTTINGER, R .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1987, 65 (09) :2118-2121

[3] ALKALOIDS OF A NEW-CALEDONIAN SEA-SQUIRT, EUDISTOMA-FRAGUM [J].

DEBITUS, C ;

LAURENT, D ;

PAIS, M .

JOURNAL OF NATURAL PRODUCTS, 1988, 51 (04) :799-801

[4]

DOI Y, 1994, TETRAHEDRON, V50, P8651, DOI 10.1016/S0040-4020(01)85338-2

[5] 6-BROMOTRYPTAMINE DERIVATIVES FROM THE GULF OF CALIFORNIA TUNICATE DIDEMNUM-CANDIDUM [J].

FAHY, E ;

POTTS, BCM ;

FAULKNER, DJ ;

SMITH, K .

JOURNAL OF NATURAL PRODUCTS, 1991, 54 (02) :564-569

[6] Marine natural products [J].

Faulkner, DJ .

NATURAL PRODUCT REPORTS, 1997, 14 (03) :259-302

[7] ELECTROSPRAY MASS-SPECTROMETRY FOR CHARACTERIZATION OF LIPID-A FROM ENTEROBACTER-AGGLOMERANS [J].

HARRATA, AK ;

DOMELSMITH, LN ;

COLE, RB .

BIOLOGICAL MASS SPECTROMETRY, 1993, 22 (01) :59-67

[8] 11-HYDROXYSTAUROSPORINE - A HIGHLY CYTOTOXIC, POWERFUL PROTEIN-KINASE-C INHIBITOR FROM A TUNICATE [J].

KINNEL, RB ;

SCHEUER, PJ .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (23) :6327-6329

[9] SHIMOFURIDIN-A, A NUCLEOSIDE DERIVATIVE EMBRACING AN ACYLFUCOPYRANOSIDE UNIT ISOLATED FROM THE OKINAWAN MARINE TUNICATE APLIDIUM-MULTIPLICATUM [J].

KOBAYASHI, J ;

DOI, Y ;

ISHIBASHI, M .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (01) :255-257

[10] PSEUDODISTOMIN-C, A NEW PIPERIDINE ALKALOID WITH UNUSUAL ABSOLUTE-CONFIGURATION FROM THE OKINAWAN TUNICATE PSEUDODISTOMA-KANOKO [J].

KOBAYASHI, J ;

NAITOH, K ;

DOI, Y ;

DEKI, K ;

ISHIBASHI, M .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (21) :6941-6945