Asymmetric synthesis of quaternary tetrahydroisoquinoline-3-carboxylic acid derivatives

被引：14

作者：

Alezra, V

Bonin, M

Micouin, L

Husson, HP

机构：

[1] CNRS, Chim Therapeut Lab, F-75270 Paris 06, France

[2] Univ Paris 05, Fac Sci Pharmaceut & Biol, F-75270 Paris, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 11期

关键词：

D O I：

10.1016/S0040-4039(01)00075-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new route towards the asymmetric preparation of quaternary 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives has been developed. The key step involves an intramolecular Pictet-Spengler reaction of an oxazolidino ester. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：2111 / 2113

页数：3

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